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以脂肪动激素/红色素浓缩激素肽家族为例的昆虫神经肽革命。

The revolution in insect neuropeptides illustrated by the adipokinetic hormone/red pigment-concentrating hormone family of peptides.

作者信息

Gäde G

机构信息

Zoology Department, University of Cape Town, Republic of South Africa.

出版信息

Z Naturforsch C J Biosci. 1996 Sep-Oct;51(9-10):607-17. doi: 10.1515/znc-1996-9-1001.

DOI:10.1515/znc-1996-9-1001
PMID:8921630
Abstract

The last decade has seen a surge in the knowledge on primary structures of insect neuropeptides. Particularly successful were isolations and sequence determinations of more than 30 members of the adipokinetic hormone/red pigment-concentrating hormone (AKH/RPCH) family of peptides. This brief overview describes the techniques used to obtain data on purification and structure such as high performance liquid chromatography, Edman sequencing and mass spectrometry. Moreover, a short account on the precursors and on the multiple functions of the peptides of the AKH/RPCH family in various crustacean and insect species is given.

摘要

在过去十年中,昆虫神经肽一级结构方面的知识激增。尤其成功的是,脂肪动激素/红色素聚集激素(AKH/RPCH)肽家族的30多个成员被分离并确定了序列。本简要概述介绍了用于获取纯化和结构数据的技术,如高效液相色谱法、埃德曼测序法和质谱分析法。此外,还简要介绍了AKH/RPCH家族肽在各种甲壳类动物和昆虫物种中的前体及其多种功能。

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