Settipane G A
Brown University School of Medicine, Providence, Rhode Island, USA.
Allergy Asthma Proc. 1996 Sep-Oct;17(5):231-6. doi: 10.2500/108854196778662246.
Nasal polyps are found in 36% of patients with aspirin intolerance, 7% of those with asthma, 0.1% in children, and about 20% in those with cystic fibrosis. Other conditions associated with nasal polyps are Churg-Strauss Syndrome, allergic fungal sinusitis, and cilia dyskinetic syndrome, (Kartagener's) and Young Syndrome. Nasal polyps are statistically more common in nonallergic asthma versus allergic asthma (13% vs 5%, P < 0.01). About 40% of patients with surgical polypectomies have recurrences. There appears to be a hereditary factor for developing nasal polyps. A classification system for staging nasal polyps is proposed in order to standardize treatment, consider differential diagnosis, and harvest meaningful comparative research information.
阿司匹林不耐受患者中36%有鼻息肉,哮喘患者中7%有鼻息肉,儿童患者中0.1%有鼻息肉,囊性纤维化患者中约20%有鼻息肉。与鼻息肉相关的其他病症有Churg-Strauss综合征、变应性真菌性鼻窦炎、纤毛运动障碍综合征(Kartagener综合征)和杨氏综合征。从统计学角度看,鼻息肉在非变应性哮喘患者中比在变应性哮喘患者中更常见(13%对5%,P<0.01)。约40%接受手术切除息肉的患者会复发。鼻息肉的发生似乎存在遗传因素。为了规范治疗、考虑鉴别诊断并获取有意义的对比研究信息,提出了一种鼻息肉分期分类系统。