Wen X, Wang X, Zhang N
Department of Materials Science and Engineering, Zhejiang University, Hangzhou, P.R. China.
Biomed Mater Eng. 1996;6(3):173-89.
In this paper, four aspects of microrough surface of metallic biomaterials are reviewed: i.e., the preparation of microrough surface, the technology of surface roughness measurement, the parameters of roughness and the bio-effect of microrough surface. Microrough surfaces (roughness below 50 microns) are easily prepared and conveniently detected in practice. Microrough surfaces allow early better adhesion of mineral ions or atoms, biomolecules, and cells, form firmer fixation of bone or connective tissue, result in thinner tissue-reaction-layer with inflammatory cells decreased or absent, and prevent microorganism adhesion and plaque accumulation, when compared with the smooth surfaces.
本文综述了金属生物材料微粗糙表面的四个方面，即微粗糙表面的制备、表面粗糙度测量技术、粗糙度参数以及微粗糙表面的生物效应。微粗糙表面（粗糙度低于50微米）在实际中易于制备且便于检测。与光滑表面相比，微粗糙表面能使矿物离子或原子、生物分子及细胞更早更好地黏附，形成更牢固的骨或结缔组织固定，使组织反应层更薄，炎症细胞减少或不存在，并防止微生物黏附和菌斑积聚。
