Semel J D, Goldin H
Section of Infectious Diseases, Rush Medical College, Chicago, Illinois, USA.
Clin Infect Dis. 1996 Nov;23(5):1162-4. doi: 10.1093/clinids/23.5.1162.
We performed a study to determine how often patients with cellulitis of the lower extremities in the absence of trauma, peripheral vascular disease, or chronic open ulcers have ipsilateral interdigital athlete's foot and whether cultures of samples from the involved interdigital spaces would yield potentially pathogenic bacteria. Athlete's foot was present in 20 (83%) of 24 episodes of cellulitis that were studied. Cultures of samples from interdigital spaces yielded Beta-hemolytic streptococci in 17 (85%) of 20 cases, Staphylococcus aureus in 9 (45%) of 20 cases, and gram-negative rods in 7 (35%) of 20 cases. Only Beta-hemolytic streptococci were recovered significantly more often from patients than from a group of controls with athlete's foot who did not have cellulitis (P < .01). Athlete's foot may be a common predisposing condition for cellulitis of the lower extremities. In comparison with attempts at microbiological diagnosis such as aspiration and/or biopsy of the area of cellulitis, cultures of samples from the interdigital spaces combined with serial determinations of antistreptolysin titers may offer a simpler noninvasive method of microbiological diagnosis.
我们进行了一项研究，以确定在无创伤、外周血管疾病或慢性开放性溃疡的情况下，下肢蜂窝织炎患者同侧指间足癣的发生频率，以及受累指间间隙样本培养是否会产生潜在病原菌。在所研究的24例蜂窝织炎发作中，20例（83%）存在足癣。指间间隙样本培养在20例中的17例（85%）检出β溶血性链球菌，20例中的9例（45%）检出金黄色葡萄球菌，20例中的7例（35%）检出革兰氏阴性杆菌。与一组无蜂窝织炎的足癣对照患者相比，仅β溶血性链球菌在患者中的检出频率显著更高（P <.01）。足癣可能是下肢蜂窝织炎常见的易感因素。与对蜂窝织炎区域进行抽吸和/或活检等微生物学诊断方法相比，指间间隙样本培养结合抗链球菌溶血素滴度的系列测定可能提供一种更简单的非侵入性微生物学诊断方法。
