Liu R S, Chu Y K, Chu L S, Yeh S H, Yen S H, Chen K Y, Chen Y K, Shen Y Y
Department of Nuclear Medicine, Taipei Veterans General Hospital, Taiwan, Republic of China.
Clin Nucl Med. 1996 Apr;21(4):302-6. doi: 10.1097/00003072-199604000-00009.
Bone scintigraphy plays an important role in the early detection of bone metastases in patients with nasopharyngeal carcinoma and serial scans may aid the clinician to assess the therapeutic response. A superscan is a pattern described as abnormal bone scan, indicating extensive bony metastases associated with various neoplastic diseases. Bone scans from 407 patients with nasopharyngeal carcinoma were reviewed retrospectively. Only six superscans (1.5%) were found. The appearance of a superscan is frequently accompanied by an abnormal titer of serological markers IgG-VCA and IgA-VCA, liver metastases, and poor survival. Although a superscan rarely occurs in nasopharyngeal carcinoma, its appearance may represent a poor prognosis in these patients.
骨闪烁扫描术在鼻咽癌患者骨转移的早期检测中起着重要作用，连续扫描有助于临床医生评估治疗反应。超级骨显像（superscan）是一种在骨扫描中描述为异常的模式，表明与各种肿瘤性疾病相关的广泛骨转移。对407例鼻咽癌患者的骨扫描进行了回顾性分析。仅发现6例超级骨显像（1.5%）。超级骨显像的出现常伴有血清学标志物IgG-VCA和IgA-VCA滴度异常、肝转移及生存率低。虽然超级骨显像在鼻咽癌中很少见，但其出现可能提示这些患者预后不良。
