Tanumihardjo S A, Suharno D, Permaesih D, Dahro A M, Karyadi D, Olson J A
Department of Food Science and Human Nutrition, Iowa State University, Ames 50011, USA.
Eur J Clin Nutr. 1995 Dec;49(12):897-903.
To determine the prevalence of subclinical vitamin A deficiency (vitamin A inadequacy) in Indonesian pregnant women as assessed by the modified relative dose response test.
Cross-sectional study of the vitamin A statuses of pregnant (second trimester) women randomly selected from ten different villages.
West Java, Indonesia.
A group of 144 pregnant women recruited from the local health posts.
Modified relative dose response (MRDR) test, serum retinol determination and gynecological examinations.
The mean (s.d.) MRDR ratio was 0.039 +/- 0.031. Of the women tested, the vitamin A status of 17% was provisionally classified as being marginal (subclinically deficient) (MRDR ratio > or = 0.060), of 35% as being uncertain (MRDR ratio between 0.030 and 0.060) and of 48% as being satisfactory (MRDR ratio < or = 0.030).
If the vitamin A statuses of the 'uncertain' group are also deemed to be unsatisfactory, approximately half of the pregnant Indonesian women tested could benefit from an increased intake of vitamin A.
通过改良相对剂量反应试验评估印度尼西亚孕妇亚临床维生素A缺乏（维生素A不足）的患病率。
对从十个不同村庄随机选取的孕妇（孕中期）的维生素A状况进行横断面研究。
印度尼西亚西爪哇。
从当地卫生站招募的144名孕妇。
改良相对剂量反应（MRDR）试验、血清视黄醇测定和妇科检查。
平均（标准差）MRDR比值为0.039±0.031。在接受检测的女性中，17%的维生素A状况被初步归类为边缘性（亚临床缺乏）（MRDR比值≥0.060），35%为不确定（MRDR比值在0.030至0.060之间），48%为满意（MRDR比值≤0.030）。
如果“不确定”组的维生素A状况也被认为不满意，那么接受检测的印度尼西亚孕妇中约有一半可能会从增加维生素A摄入量中受益。
