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用于治疗良性前列腺增生症的434兆赫经尿道系统的加热特性及组织间温度测量

Heating characteristics of a 434 MHz transurethral system for the treatment of BPH and interstitial thermometry.

作者信息

Venn S N, Hughes S W, Montgomery B S, Timothy A

机构信息

Department of Urology, Radiotherapy and Medical Physics, St. Thomas' Hospital, London, UK.

出版信息

Int J Hyperthermia. 1996 Mar-Apr;12(2):271-8. doi: 10.3109/02656739609022514.

Abstract

A system is described for delivering transurethral hyperthermia to the prostate. The system used a helical coil antennae powered by a 434 MHz generator. The antennae was housed in a disposable 22 Ch Foley catheter with water passed down the centre of the winding of the antennae and returned between the antennae and inner wall of the catheter. The flow rate of the circulating water could be varied. The position of the antennae was adjustable with respect to the balloon, essentially altering the length of the antennae. Urethral wall temperature was measured with a thermocouple passed down a small tube moulded into the outer wall of the catheter. Rectal temperature was measured using thermocouples placed in grooves machined into a custom made perspex rectal applicator. A computer program displayed the temperature and controlled the power to the generator. The SAR around the catheter was measured in a polyacrylamide gel phantom. However this does not take into account the effects blood flow and thermal conduction which may have important clinical implications. In order to investigate the actual temperature within the prostate during treatment, a group of patients underwent intraprostatic thermometry.

摘要

描述了一种用于向前列腺输送经尿道热疗的系统。该系统使用由434兆赫发生器供电的螺旋线圈天线。天线安装在一次性22腔Foley导管中,水沿天线绕组中心向下流动,并在天线与导管内壁之间回流。循环水的流速可以变化。天线相对于球囊的位置是可调节的,本质上改变了天线的长度。尿道壁温度通过沿模制在导管外壁的小管向下传递的热电偶进行测量。直肠温度通过放置在定制有机玻璃直肠施药器上加工的凹槽中的热电偶进行测量。一个计算机程序显示温度并控制发生器的功率。在聚丙烯酰胺凝胶模型中测量了导管周围的比吸收率(SAR)。然而,这没有考虑到血流和热传导的影响,而这些影响可能具有重要的临床意义。为了研究治疗期间前列腺内的实际温度,一组患者接受了前列腺内温度测量。

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