Astrahan M A, Sapozink M D, Cohen D, Luxton G, Kampp T D, Boyd S, Petrovich Z
Department of Radiation Oncology, University of Southern California School of Medicine, Kenneth Norris Cancer Hospital, Los Angeles 90033.
Int J Hyperthermia. 1989 May-Jun;5(3):283-96. doi: 10.3109/02656738909140455.
An applicator for heating the prostate gland using a transurethral approach is described. This technique uses three microwave antennas and a thermometry sensor attached to the outer surface of a balloon (Foley) type urological catheter. Each microwave antenna also includes a built-in thermistor to control temperature and balance power. The balloon catheter assures rapid and reproducible localization of the antennas in the prostatic urethra. The two-dimensional SAR and steady-state temperature distributions surrounding the applicator in tissue equivalent phantom are reported. Longitudinal temperature distributions measured in situ at the applicator-urethral interface and the longitudinal and radial temperature distributions measured in normal canine prostate are presented and discussed. The technique appears to be capable of elevating temperature to greater than 42 degrees C in a cylindrically symmetrical volume up to 5 cm length and 0.5 cm radial penetration surrounding the applicator.
描述了一种使用经尿道方法加热前列腺的施药器。该技术使用三个微波天线和一个连接到球囊（弗利氏）型泌尿科导管外表面的温度测量传感器。每个微波天线还包括一个内置热敏电阻，用于控制温度和平衡功率。球囊导管确保天线在前列腺尿道中快速且可重复定位。报告了在组织等效体模中施药器周围的二维比吸收率（SAR）和稳态温度分布。给出并讨论了在施药器-尿道界面原位测量的纵向温度分布以及在正常犬前列腺中测量的纵向和径向温度分布。该技术似乎能够在围绕施药器的长度达5厘米、径向穿透达0.5厘米的圆柱形对称体积内将温度升高到42摄氏度以上。
