[上呼吸道相关疾病患者支气管哮喘的病程特征]

[Characteristics of the course of bronchial asthma in patients with associated diseases of the upper respiratory tract].

作者信息

Makolkin V I, Chichkova N V, Ovcharenko S I

出版信息

Klin Med (Mosk). 1996;74(3):39-42.

Abstract

The examination of 56 patients (35 females and 21 males) with bronchial asthma (BA) associated with nasal and paranasal diseases revealed allergic rhinosinusopathy (ARSP) in 87.5% of the examinees. Nasal and paranasal affections in BA of bacterial and atopic genesis differed. The study of external respiration showed that its volume and rate abnormality increased with growing severity of nasal and paranasal affections. The results of cytological investigations of impression smears of the nasal mucosa, sputum and bronchial lavage (portion I and II) suggest that elevated levels of eosinophilic leukocytes in all the studied specimens in BA patients with ARSP may evidence for common character of allergic reactions in the above nasal and bronchial diseases.

摘要

对56例（35名女性和21名男性）患有与鼻及鼻窦疾病相关的支气管哮喘（BA）患者进行检查，结果显示87.5%的受检者存在变应性鼻鼻窦炎（ARSP）。细菌性和特应性病因所致BA中的鼻及鼻窦病变有所不同。对外呼吸的研究表明，其容量和速率异常随着鼻及鼻窦病变严重程度的增加而加重。对鼻黏膜、痰液及支气管灌洗（第一部分和第二部分）印片的细胞学研究结果表明，ARSP的BA患者所有研究标本中嗜酸性白细胞水平升高，可能证明上述鼻和支气管疾病中过敏反应具有共同特征。