Faravelli A, Gambini S, Perego D, Nobili R, Zoldan M C, Leone B E, Giani L
Servizio di Anatomia Patologica, Ospedale Desio, Milano.
Pathologica. 1995 Dec;87(6):692-5.
A case of Primary Malignant Lymphoma of the Spleen (PMLS) with exclusive red pulp involvement is described and discussed. Although the unusual topographic presentation the authors emphasize the physiologic arrangement of lymphoid cell in splenic red pulp cords that can give origin to the neoplasia. They moreover discuss problems of differential diagnosis with Malignant Histiocytosis (MH), Hairy Cell Leukemia (HCL) and Myeloid Process, both by morphology and immunohistochemistry.
本文描述并讨论了一例仅累及脾红髓的原发性脾恶性淋巴瘤（PMLS）。尽管其具有不寻常的拓扑学表现，但作者强调脾红髓索中淋巴样细胞的生理排列可能是肿瘤发生的起源。此外，他们还通过形态学和免疫组织化学讨论了与恶性组织细胞增多症（MH）、毛细胞白血病（HCL）和髓系病变进行鉴别诊断的问题。
