Szulkowska E, Zygocki K, Sułek K
V Kliniki Chorób Wewnetrznych IMW CSK WAM w Warszawie.
Pol Tyg Lek. 1996 Mar;51(10-13):179-81.
The laser Doppler flowmetry is a new technique for evaluating microcirculation. It is based on the Doppler phenomenon-reflected light changes its frequency when it interacts with moving objects such as red blood cells. The source of light is 2 mW He-Ne laser. The light penetrates into the tissue to the depth of 1 mm, and measures microvascular blood flow throughout it. This technique is objective, harmless even during prolonged exposition, repeatable, and very sensitive even to small changes in the blood flow. Because of difficulties with determination of the perfusion normal values and several factors disturbing microcirculation, the most objective results are obtained with dynamic tests. They measure a response of microcirculation to local ischemia, cooling or given medicines. A disadvantage is its high sensitivity to motion-produced disturbances. Laser Doppler flowmetry may be used not only in scientific investigations. It is of diagnostic value in plastic surgery, vascular surgery, dermatology, internal medicine, dentistry, and neurology.
激光多普勒血流仪是一种评估微循环的新技术。它基于多普勒现象——反射光在与诸如红细胞等移动物体相互作用时会改变其频率。光源是2毫瓦的氦氖激光器。光穿透组织达1毫米深度，并测量整个组织中的微血管血流。该技术客观、即使长时间暴露也无害、可重复，并且对血流的微小变化非常敏感。由于确定灌注正常值存在困难以及有多种因素干扰微循环，动态测试能获得最客观的结果。动态测试测量微循环对局部缺血、冷却或给予药物的反应。一个缺点是它对运动产生的干扰高度敏感。激光多普勒血流仪不仅可用于科学研究。它在整形外科、血管外科、皮肤科、内科、牙科和神经科具有诊断价值。
