Caulet S, Robert I, Bardaxoglou E, Noret P, Tas P, Le Prise Y, Launois B, Ramee M P
Department of Pathology B, Pontchaillou Hospital, Rennes, France.
Pathol Res Pract. 1995 Dec;191(12):1203-7. doi: 10.1016/S0344-0338(11)81127-1.
Non Hodgkin Malignant lymphomas (NHML) of mucosa associated lymphoid tissue (MALT) are known to have multiple involvement of the digestive tract. We report one case, presenting with an infiltrative process of the jejuno-ileum, associating lymphoplasmacytoid proliferating cells and amyloidosis. The plasmacytoid cells expressed Alpha and scarce Mu heavy chains, and lambda light chain. Lympho-epithelial lesions were more obvious at the second site of involvement, in the gastric mucosa. The amyloid substance was negative with the Amyloid A component antibody and gave a background noise with Alpha, Mu and lambda chains. No similar report of amyloidosis associated with MALT NHML has been found in the literature.
已知黏膜相关淋巴组织（MALT）的非霍奇金恶性淋巴瘤（NHML）可累及消化道多处。我们报告1例空肠回肠浸润性病变病例，伴有淋巴浆细胞样增殖细胞及淀粉样变性。浆细胞样细胞表达α和少量μ重链以及λ轻链。在第二个受累部位胃黏膜中，淋巴上皮病变更为明显。淀粉样物质对淀粉样蛋白A成分抗体呈阴性，对α、μ和λ链呈背景噪声。文献中未发现与MALT NHML相关的淀粉样变性的类似报告。
