Ruppe A, Keller F, Wolfersdorf M
Abt. Psychiatrie I der Universität Ulm, AG Verlaufsforschung, Bereich Akutpsychiatrie II/Depression, Ravensburg.
Psychiatr Prax. 1996 Jul;23(4):175-9.
A 6-year follow-up study of unipolar depressive inpatients shows a high percentage of 26% of patients with a chronic course. The chronic patients have significant longer phases of depression in the history of their illness or in the index episode and a longer hospitalisation in the index episode. Patients with chronic course have although more often a first episode before the age of 25 years, were less suicidal by admission to hospital and show less improvement from admission to discharge. The study shows, that although not all aspects of the clinical course are related with chronicity, the duration of depressive phases is a good predictor for a chronic course.
一项针对单相抑郁住院患者的6年随访研究显示，26%的患者病程呈慢性，比例较高。慢性病程患者在其疾病史或本次发作中有明显更长的抑郁期，且本次发作的住院时间更长。病程呈慢性的患者虽然更常在25岁之前首次发作，入院时自杀倾向较低，且从入院到出院的改善程度较小。该研究表明，虽然临床病程的并非所有方面都与慢性病程相关，但抑郁期的时长是慢性病程的一个良好预测指标。
