Rokosz A, Rafałowska K, Lipnicki D
Zakład Bakteriologii Klinicznej AM w Warszawie.
Przegl Epidemiol. 1996;50(3):265-72.
4608 clinical specimens (including 1641 samples of blood) for bacteriological examination were obtained from patients hospitalized in different wards of National Clinical Hospital No 1 in Warsaw. Strains were cultured, identified and their sensitivity to antibacterial drugs was determined during 14 months with the use of semi-automated API (ATB-plus) system (bioMérieux, France). Strains of Gram-positive, catalase-negative cocci were separated from all cultured strains. They belonged to the genera: Streptococcus, Enterococcus, Gemella, Aerococcus and Lactococcus (538 strains altogether). 238 Streptococcus spp. strains (44.2%) and 201 Enterococcus spp. strains (37.4%)were isolated from all specimens. The greatest number of catalase-negative cocci was obtained from wound smears -420 strains, which amounts to 78.2% of all strains. Among isolates dominated E. faecalis strains -104 (19.3%) and E. faecium strains - 70 (13.0% of all isolated strains). Vancomycin was the most effective antibacterial drug against gram-positive, catalase-negative cocci isolated from patients hospitalized in our hospital. Vancomycin-resistant strains constituted from 3% to 18% of strains depending on a species.
从华沙第一国立临床医院不同病房住院的患者中获取了4608份用于细菌学检查的临床标本(包括1641份血液样本)。在14个月期间,使用半自动API(ATB-plus)系统(法国生物梅里埃公司)对菌株进行培养、鉴定并测定其对抗菌药物的敏感性。从所有培养菌株中分离出革兰氏阳性、过氧化氢酶阴性球菌菌株。它们属于以下属:链球菌属、肠球菌属、孪生球菌属、气球菌属和乳球菌属(共538株)。从所有标本中分离出238株链球菌属菌株(44.2%)和201株肠球菌属菌株(37.4%)。过氧化氢酶阴性球菌数量最多的是伤口涂片——420株,占所有菌株的78.2%。分离菌株中粪肠球菌菌株占主导——104株(19.3%),屎肠球菌菌株——70株(占所有分离菌株的13.0%)。万古霉素是针对我院住院患者分离出的革兰氏阳性、过氧化氢酶阴性球菌最有效的抗菌药物。万古霉素耐药菌株占菌株的3%至18%,具体取决于菌种。