Kristensen J, Langhoff-Roos J, Kristensen F B
Rigshospitalet, København, Juliane Marie Centret, føde og gynaekologisk afdeling.
Ugeskr Laeger. 1996 Sep 23;158(39):5443-6.
The objective of the study was to characterize and quantify various demographic factors in idiopathic preterm delivery. All women with a permanent address in Denmark with singleton pregnancies who gave birth to an infant in 1982 (n = 51,851) are included. The material was obtained by a linkage of the Medical Birth Register and the National Register of Hospital Discharges, using the personal identification number. The incidence of singleton preterm delivery was 4.5% (n = 2330) of which 67% (n = 1557) were idiopathic. Neonatal mortality rates were significantly lower in idiopathic compared to indicated preterm birth. Following stepwise logistic regression analysis, maternal age below 20 (adjusted odds ratio 1.63, 95% confidence interval (CI) 1.07-2.47; p < 0.03), maternal age above 30 (adjusted odds ratio 0.74, 95% CI 0.60-0.90; p < 0.004) and being married (adjusted odds ratio 0.63, 95% CI 0.43-0.94; p < 0.03) correlated with idiopathic preterm birth. It is concluded that idiopathic preterm birth is more common in single, young women and associated with lower neonatal mortality rate than indicated preterm birth.
该研究的目的是描述和量化特发性早产的各种人口统计学因素。纳入了所有1982年在丹麦有常住地址、单胎妊娠并分娩婴儿的妇女（n = 51,851）。通过使用个人识别码将医疗出生登记册和国家医院出院登记册相链接获取相关资料。单胎早产的发生率为4.5%（n = 2330），其中67%（n = 1557）为特发性。与指征性早产相比，特发性早产的新生儿死亡率显著更低。经过逐步逻辑回归分析，母亲年龄低于20岁（调整后的优势比为1.63，95%置信区间（CI）为1.07 - 2.47；p < 0.03）、母亲年龄高于30岁（调整后的优势比为0.74，95% CI为0.60 - 0.90；p < 0.004）以及已婚（调整后的优势比为0.63，95% CI为0.43 - 0.94；p < 0.03）与特发性早产相关。得出的结论是，特发性早产在单身年轻女性中更为常见，且与指征性早产相比，其新生儿死亡率更低。
