Raeman C H, Child S Z, Dalecki D, Cox C, Carstensen E L
Department of Biostatistics, University of Rochester, NY 14627, USA.
Ultrasound Med Biol. 1996;22(1):139-41. doi: 10.1016/0301-5629(95)02036-5.
Although the extent of suprathreshold damage to murine lung that results from exposure to pulsed ultrasound increases with time, the threshold level for lung hemorrhage is relatively insensitive to total exposure time. Adult mice were exposed for 20 s and 3 min to 2.3-MHz ultrasound (10-microseconds pulses, 100-Hz pulse repetition frequency) at peak positive pressures ranging up to 3 MPa. Threshold pressures for the two exposure times, 1.6 MPa and 1.4 MPa, respectively, are the same within the statistical significance of the measurements.
