Lozovksaia L S, Soboleva V D, Iakovleva A A
Vopr Virusol. 1996 May-Jun;41(3):122-6.
Coxsackie group enteroviruses, mainly Coxsackie A13 virus, were detected in involved joints of 76% children with rheumatoid arthritis, adenoviruses (mainly adenovirus 5) in 68%, and rubella virus in 52%. Mixed virus infection was diagnosed in 80% patients. At least one of the above viruses was detected in 23 out of 25 examinees (92%). The authors discuss the contribution of different viruses to the etiology of juvenile rheumatoid arthritis and consider that chronic Coxsackie virus infection is the most probable primary etiological factor of this disease.
在患类风湿性关节炎的儿童中，76%的患儿受累关节检测到柯萨奇肠道病毒群，主要是柯萨奇A13病毒；68%检测到腺病毒（主要是腺病毒5型）；52%检测到风疹病毒。80%的患者被诊断为混合病毒感染。25名受检者中有23名（92%）检测到至少上述一种病毒。作者讨论了不同病毒在青少年类风湿性关节炎病因中的作用，并认为慢性柯萨奇病毒感染最有可能是该病的主要病因。
