Kharchenko V P, Galil-Ogly G A, Gudov V F, Parkhomenko A A
Arkh Patol. 1996 Jan-Feb;58(1):70-4.
Regular investigations on application of hyperthermia in oncology have been carried out since the second half of the 1950s. The usage of distant tissues heating faces considerable difficulties in maintenance of therapeutic temperature in the whole volume of the tumor. Thus, the use of interstitial hyperthermia is promising, especially, ferromagnetic hyperthermia which causes damage not only to central but also to peripheral zones of tumors. Light and electron microscopies have not revealed specific features of cell damage by which ferromagnetic hyperthermia might differ from other methods of antitumor treatment.
自20世纪50年代后半期以来，一直在对热疗在肿瘤学中的应用进行定期研究。远距离组织加热在维持肿瘤整个体积的治疗温度方面面临相当大的困难。因此，间质热疗的应用前景广阔，尤其是铁磁热疗，它不仅会对肿瘤的中心区域造成损伤，还会对周边区域造成损伤。光学显微镜和电子显微镜检查均未发现铁磁热疗导致细胞损伤的特定特征，而这些特征可能使铁磁热疗有别于其他抗肿瘤治疗方法。
