Gottsauner-Wolf M, Schedlmayer-Duit J, Porenta G, Gwechenberger M, Huber K, Glogar D, Probst P, Sochor H
Department of Cardiology, University of Vienna, Waehringer Guertel 18-20, A-1090 Vienna, Austria.
Eur J Nucl Med. 1996 Dec;23(12):1613-8. doi: 10.1007/BF01249624.
Measurement of global left ventricular function is important in the follow-up of cardiac patients and is a good prognostic indicator in acute cardiac situations. We compared quantitative measurements of global left ventricular function made with radionuclide angiography (RNA) and contrast cardiac ventriculography (CVG) to visual semiquantitative estimates from two-dimensional echocardiographic images (2D-echo). Three hundred and thirty-nine consecutive patients who underwent RNA were assessed with 2D-echo within 3 months. In addition, 92 of these patients also underwent CVG (correlation of ejection fraction between CVG and RNA: r=0.82; P<0.0001). The RNA mean ejection fractions in the four 2D-echo groups (0=normal, 1=slightly, 2=moderate, or 3=severe reduced left ventricular function) differed markedly (P<0.0001); however, there was overlapping among the groups (2D-echo score/RNA ejection fraction: 0=57.3%+/-12.8%; 1=46.0%+/-12.9%; 2=29.6%+/- 12.2%; and 3=24.6%+/-11. 5%) and the difference between 2D-echo scores 2 and 3 was not significant. 2D-echo showed a good concordance in RNA classes (0=>/=505; 1=35%-49%; 2=21%-34%; and 3=</=20% ejection fraction) 0 (133/166; 80%) and 3 (18/30; 60%) but low concordance in classes 1 (27/82; 33%) and 2 (21/61; 34%). For accurate assessment of global left ventricular ejection fraction, visual semiquantitative judgement of a 2D echocardiographic image is limited in comparison to CVG or RNA, especially in patients with a slight or moderate reduction in left ventricular ejection fraction.
左心室整体功能的测量对于心脏病患者的随访很重要，并且在急性心脏疾病情况下是一个良好的预后指标。我们比较了放射性核素血管造影（RNA）和对比剂心室造影（CVG）对左心室整体功能的定量测量结果与二维超声心动图图像（2D-回声）的视觉半定量评估。339例连续接受RNA检查的患者在3个月内接受了2D-回声评估。此外，其中92例患者还接受了CVG检查（CVG与RNA之间射血分数的相关性：r = 0.82；P <0.00０1）。四个2D-回声组（0 =正常，1 =轻度，2 =中度，或3 =左心室功能严重降低）的RNA平均射血分数有显著差异（P <0.00０1）；然而，各组之间存在重叠（2D-回声评分/RNA射血分数：0 = 57.3%±12.8%；1 = 46.0%±12.9%；2 = 29.6%±12.2%；3 = 24.6%±11.5%），且2D-回声评分2和3之间的差异不显著。2D-回声在RNA类别（0 =≥50%；1 = 35%-49%；2 = 21%-34%；3 =≤20%射血分数）0（133/166；80%）和3（18/30；60%）中显示出良好的一致性，但在类别1（27/82；33%）和2（21/61；34%）中一致性较低。对于左心室整体射血分数的准确评估，与CVG或RNA相比，二维超声心动图图像的视觉半定量判断是有限的，尤其是在左心室射血分数轻度或中度降低的患者中。
