糖尿病肾病

Diabetic nephropathy.

作者信息

Groggel G C

机构信息

Department of Internal Medicine, University of Nebraska Medical Center, Omaha, USA.

出版信息

Arch Fam Med. 1996 Oct;5(9):513-20; discussion 521. doi: 10.1001/archfami.5.9.513.

DOI:10.1001/archfami.5.9.513

PMID:8930222

Abstract

Diabetic nephropathy is an important microvascular complication of both insulin-dependent and non-insulin-dependent diabetes mellitus. It is the leading cause of end-stage renal disease. The natural course, pathogenesis, clinical evaluation, and treatment of diabetic nephropathy were reviewed, with special emphasis on recent important studies of glucose control and use of the angiotensin-converting enzyme inhibitors in the treatment of diabetic nephropathy.

摘要

糖尿病肾病是胰岛素依赖型和非胰岛素依赖型糖尿病的一种重要微血管并发症。它是终末期肾病的主要病因。本文综述了糖尿病肾病的自然病程、发病机制、临床评估和治疗，特别强调了近期关于血糖控制以及血管紧张素转换酶抑制剂在糖尿病肾病治疗中的应用的重要研究。