Smith S T, Stackman R W, Clark A S
Department of Physiology, Dartmouth Medical School, Hanover, NH 03755, USA.
Brain Res. 1996 Oct 21;737(1-2):313-6. doi: 10.1016/0006-8993(96)00932-8.
The effects of anabolic-androgenic steroid (AAS) compounds on spatial working memory were evaluated in male rats. Thirty days of administration of a high dose of three individual AAS compounds (17 alpha-methyltestosterone, methandrostenolone, or testosterone cypionate) had no effects on spatial memory or motivation as tested on a delayed non-match-to-sample radial arm maze task. Administration of these AAS compounds at doses within the human abuse range does not impair spatial working memory in rats.
在雄性大鼠中评估了合成代谢雄激素类固醇（AAS）化合物对空间工作记忆的影响。连续30天给予高剂量的三种单独的AAS化合物（17α-甲基睾酮、大力补或环戊丙酸睾酮），在延迟非匹配样本放射状臂迷宫任务测试中，对空间记忆或动机没有影响。以人类滥用范围内的剂量给予这些AAS化合物不会损害大鼠的空间工作记忆。
