Bae H S, Lee J M, Lee S T
Department of Biological Sciences, Korea Advanced Institute of Science and Technology, Taejun, South Korea.
FEMS Microbiol Lett. 1996 Nov 15;145(1):125-9. doi: 10.1111/j.1574-6968.1996.tb08566.x.
A newly isolated Arthrobacter ureafaciens, strain CPR706, could degrade 4-chlorophenol via a new pathway, in which the chloro-substituent was eliminated in the first step and hydroquinone was produced as a transient intermediate. Strain CPR706 exhibited much higher substrate tolerance and degradation rate than other strains that degraded 4-chlorophenol by the hydroxylation at the second carbon position to form chlorocatechol. Strain CPR706 could also degrade other para-substituted phenols (4-nitro-, 4-bromo-, 4-iodo-, and 4-fluoro-phenol) via the hydroquinone pathway.
新分离出的一株脲芽胞八叠球菌CPR706，可通过一条新途径降解4-氯苯酚，该途径的第一步是去除氯取代基，并产生对苯二酚作为瞬时中间体。与其他通过在第二个碳位置羟基化形成氯儿茶酚来降解4-氯苯酚的菌株相比，CPR706菌株表现出更高的底物耐受性和降解率。CPR706菌株还可通过对苯二酚途径降解其他对取代酚（4-硝基苯酚、4-溴苯酚、4-碘苯酚和4-氟苯酚）。
