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腹腔镜下微波热疗治疗小肾癌:利用兔VX-2移植瘤的实验研究

Laparoscopic microwave thermotherapy on small renal tumors: experimental studies using implanted VX-2 tumors in rabbits.

作者信息

Kigure T, Harada T, Yuri Y, Satoh Y, Yoshida K

机构信息

Department of Urology, Akita University School of Medicine, Japan.

出版信息

Eur Urol. 1996;30(3):377-82. doi: 10.1159/000474199.

DOI:10.1159/000474199
PMID:8931973
Abstract

OBJECTIVE

To investigate the effectiveness of microwave thermotherapy on implanted renal VX-2 tumors.

METHODS

Fifteen rabbits with implanted renal VX-2 tumors were divided into three groups according to the type of therapy: nephrectomy, laparoscopic microwave thermotherapy, and no treatment. Both the anticancer effect and safety were compared among these groups.

RESULTS

The survival rate in the laparoscopic microwave thermotherapy group was significantly higher than that in the no-treatment group, and was the same as that in the nephrectomy group. The serum creatinine level did not increase after microwave therapy.

CONCLUSION

Laparoscopic microwave thermotherapy may be useful for a nephron-salvaging treatment in small implanted renal VX-2 tumors in rabbits.

摘要

目的

探讨微波热疗对兔植入性肾VX-2肿瘤的疗效。

方法

将15只植入肾VX-2肿瘤的兔根据治疗方式分为三组:肾切除术、腹腔镜微波热疗和不治疗。比较三组的抗癌效果和安全性。

结果

腹腔镜微波热疗组的生存率显著高于不治疗组,与肾切除组相同。微波治疗后血清肌酐水平未升高。

结论

腹腔镜微波热疗可能有助于对兔小植入性肾VX-2肿瘤进行保肾单位治疗。

相似文献

1
Laparoscopic microwave thermotherapy on small renal tumors: experimental studies using implanted VX-2 tumors in rabbits.腹腔镜下微波热疗治疗小肾癌:利用兔VX-2移植瘤的实验研究
Eur Urol. 1996;30(3):377-82. doi: 10.1159/000474199.
2
Third Prize: Comparison of radical nephrectomy, laparoscopic microwave thermotherapy, cryotherapy, and radiofrequency ablation for destruction of experimental VX-2 renal tumors in rabbits.三等奖:根治性肾切除术、腹腔镜微波热疗、冷冻疗法及射频消融术对兔VX-2肾肿瘤实验性破坏的比较
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Ultrasound-guided microwave thermotherapy on a VX-2 carcinoma implanted in rabbit kidney.超声引导下对兔肾移植VX-2癌进行微波热疗。
Ultrasound Med Biol. 1995;21(5):649-55. doi: 10.1016/0301-5629(95)00008-f.
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Experimental study of microwave coagulation of a VX-2 carcinoma implanted in rabbit kidney.
Int J Urol. 1994 Mar;1(1):23-7. doi: 10.1111/j.1442-2042.1994.tb00003.x.
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[Intracavitary and interstitial hyperthermia with the 2 mm diameter microwave applicator].
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Microwave ablation of renal parenchymal tumors before nephrectomy: phase I study.肾切除术前行肾实质肿瘤微波消融:I期研究
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Laparoscopic partial nephrectomy using microwave tissue coagulator for small renal tumors: usefulness and complications.使用微波组织凝固器进行腹腔镜下小肾肿瘤部分肾切除术:实用性与并发症
Eur Urol. 2004 Jun;45(6):744-8. doi: 10.1016/j.eururo.2004.02.007.
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