枯草芽孢杆菌的SpoIIAA蛋白具有GTP结合特性。
The SpoIIAA protein of Bacillus subtilis has GTP-binding properties.
作者信息
Najafi S M, Harris D A, Yudkin M D
机构信息
Department of Biochemistry, University of Oxford, United Kingdom.
出版信息
J Bacteriol. 1996 Nov;178(22):6632-4. doi: 10.1128/jb.178.22.6632-6634.1996.
Abstract
SpoIIAA is the first protein of the spoIIA operon. Here we show that SpoIIAA can bind and hydrolyze GTP. The protein also accepts ATP, but with lower affinity. GDP competes poorly for binding of GTP. The GTPase activity of SpoIIAA is within the range found for other GTP-binding proteins.
摘要
SpoIIAA是spoIIA操纵子的首个蛋白质。我们在此表明，SpoIIAA能够结合并水解GTP。该蛋白质也能接受ATP，但亲和力较低。GDP对GTP结合的竞争能力较弱。SpoIIAA的GTP酶活性处于其他GTP结合蛋白的活性范围内。
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