Grossman P, Hagel K
Arzt fur Neurologie un Psychiatrie, Neurologische Klinik Elzach/Schwarzwald, Postfach, Germany.
Disabil Rehabil. 1996 Jan;18(1):1-20. doi: 10.3109/09638289609167084.
Epidemiological studies made within the western countries indicate an incidence of 200-300 traumatic head injuries per 100 000 residents each year. Severe head injuries account for 5-25% of all head injuries; 10-14% of all severe head-injured patients develop into a vegetative state, in which a sleep-wake rhythm is apparent, but however in which there is no evidence of awakeness or reactivity to the environment. The most commonly used labels, in the German and international literature, for these patients are 'vegetative state', 'apallic syndrome' and 'coma vigile'. This clinical characterization is not sufficient. It is necessary to employ additional criteria to distinguish subsets of vegetative patients e.g. computerized tomography, magnetic resonance imaging, single photon emission tomography, electroencephalography, brainstem reflexes, evoked potentials, assessment scales, age, premorbid brain disorders. Diagnostic and prognostic parameters must form the basis for various decisions relating to patients' care and intervention.
西方国家开展的流行病学研究表明,每年每10万居民中创伤性颅脑损伤的发生率为200 - 300例。重度颅脑损伤占所有颅脑损伤的5% - 25%;所有重度颅脑损伤患者中有10% - 14%会发展为植物状态,即存在明显的睡眠 - 觉醒节律,但没有清醒或对环境有反应的证据。在德语和国际文献中,针对这些患者最常用的术语是“植物状态”“无动性缄默综合征”和“醒状昏迷”。这种临床特征描述并不充分。有必要采用额外的标准来区分植物状态患者的亚组,例如计算机断层扫描、磁共振成像、单光子发射断层扫描、脑电图、脑干反射、诱发电位、评估量表、年龄、病前脑部疾病。诊断和预后参数必须作为与患者护理和干预相关的各种决策的依据。