Blijenberg B G, Kranse R, Eman I, Schröder F H
Department of Clinical Chemistry, University Hospital Rotterdam, The Netherlands.
Eur J Clin Chem Clin Biochem. 1996 Oct;34(10):817-21. doi: 10.1515/cclm.1996.34.10.817.
In this study, various analytical aspects of the determination of serum prostate-specific antigen are described as applied to the Abbott IMx PSA and the Hybritech Tandem-E PSA assays. We used mainly specimens from a prostate cancer screening study in progress. A very good comparability between the assays proved to exist in our hands. The long-run variation (16 months) was also rated as acceptable, both for the IMx and the Tandem-E method. The method of choice, Tandem-E, showed good reagent stability over this period. We found, however, a difference in accuracy (Tandem-E +/- 8% higher values) that could not be explained by comparison with Tandem-R.
在本研究中，描述了血清前列腺特异性抗原测定的各种分析方面，这些方面应用于雅培IMx PSA和Hybritech Tandem-E PSA检测。我们主要使用了来自正在进行的前列腺癌筛查研究的标本。在我们手中，这两种检测方法之间显示出非常好的可比性。IMx和Tandem-E方法的长期变异（16个月）也被评定为可接受。所选择的方法Tandem-E在这段时间内显示出良好的试剂稳定性。然而，我们发现准确性存在差异（Tandem-E的值高±8%），与Tandem-R比较无法解释这种差异。
