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侵袭性非霍奇金淋巴瘤伴右心室大量受累。

Aggressive non-Hodgkin's lymphoma with massive involvement of the right ventricle.

作者信息

Tanaka T, Sato T, Akifuji Y, Sakamoto M, Shio H, Ueki J, Taniguchi I, Nakamoto S

机构信息

Department of Internal Medicine, Tottori Prefectural Central Hospital.

出版信息

Intern Med. 1996 Oct;35(10):826-30. doi: 10.2169/internalmedicine.35.826.

DOI:10.2169/internalmedicine.35.826
PMID:8933196
Abstract

A 69-year-old women with malignant lymphoma (diffuse large:Working formulation) had associated with intracavital involvement of the right ventricle. The patient was referred to us for further examination with a diagnosis of heart failure. A tumor mass was detected by magnetic resonance imaging in the right ventricular outflow tract. While in the hospital the patient experienced cardiogenic shock due to neoplastic pulmonary embolism. The tumor was surgically resected and the patient was then treated with systemic chemotherapy. She went into complete remission and has continued in this state for six months. This case demonstrates that early diagnosis and intensive chemotherapy contribute to a good prognosis of patients with malignant lymphoma associated with massive involvement of a cardiac chamber. A review of the Japanese literature is presented.

摘要

一名69岁患有恶性淋巴瘤(弥漫大细胞型:工作分类法)的女性伴有右心腔内受累。该患者因心力衰竭诊断被转诊至我院进一步检查。磁共振成像在右心室流出道检测到一个肿瘤肿块。住院期间,患者因肿瘤性肺栓塞发生心源性休克。肿瘤被手术切除,随后患者接受全身化疗。她实现了完全缓解,并持续这种状态六个月。该病例表明,早期诊断和强化化疗有助于改善伴有心脏腔室大量受累的恶性淋巴瘤患者的预后。现对日本文献进行综述。

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Aggressive non-Hodgkin's lymphoma with massive involvement of the right ventricle.侵袭性非霍奇金淋巴瘤伴右心室大量受累。
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Am J Case Rep. 2018 Sep 4;19:1057-1062. doi: 10.12659/AJCR.910787.
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High-dose chemotherapy with autologous stem cell transplantation following systemic chemotherapy, prophylactic intrathecal methotrexate, and radiotherapy prevents relapse and improves the outcome of advanced stage primary testicular lymphoma even with cardiac involvement.全身化疗、鞘内预防性注射甲氨蝶呤及放疗后行大剂量化疗联合自体干细胞移植,即使存在心脏受累情况,也可预防晚期原发性睾丸淋巴瘤复发并改善其预后。
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