Pendlebury S, Horwich A, Dearnaley D P, Nicholls J, Fisher C
Royal Prince Alfred Hospital, Sydney, Australia.
Clin Oncol (R Coll Radiol). 1996;8(5):316-8. doi: 10.1016/s0936-6555(05)80719-8.
Spermatocytic seminoma is an uncommon variety of testicular neoplasm, differing from its classical counterpart at both clinical and pathological levels and having a low propensity to metastasize. This is a retrospective review of ten patients with pathologically confirmed and reviewed disease who were seen at the Royal Marsden Hospital. All patients presented as Stage I. Five were treated with radiotherapy and five have undergone surveillance. The median age was 56.5 years. The median follow-up is 8 years and no patient has relapsed. Two have died of intercurrent disease. Our series supports others of a similar size in the literature with respect to both the rarity and the good prognosis of spermatocytic seminoma. With only one case of relapse confirmed in the literature, this is a subgroup of patients in whom radiotherapy can safely be omitted.
精母细胞性精原细胞瘤是一种罕见的睾丸肿瘤,在临床和病理层面均与经典型精原细胞瘤不同,且转移倾向较低。本文对10例经病理确诊并经复查的患者进行了回顾性研究,这些患者均在皇家马斯登医院就诊。所有患者初诊时均为Ⅰ期。5例接受了放疗,5例接受了观察等待。中位年龄为56.5岁。中位随访时间为8年,无患者复发。2例死于并发疾病。我们的系列研究在精母细胞性精原细胞瘤的罕见性和良好预后方面与文献中其他规模相似的研究结果一致。鉴于文献中仅证实有1例复发,对于这一亚组患者,可以安全地省略放疗。