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猪体内对用作腹膜前植入物的单丝和编织聚丙烯网的异物反应。

Foreign body reactions to monofilament and braided polypropylene mesh used as preperitoneal implants in pigs.

作者信息

Beets G L, Go P M, van Mameren H

机构信息

Department of Surgery, University Hospital Maastricht, The Netherlands.

出版信息

Eur J Surg. 1996 Oct;162(10):823-5.

PMID:8934114
Abstract

OBJECTIVES

To compare the foreign body reaction of the monofilament polypropylene (Prolene) mesh, and the multifilament Surgipro mesh. Both types of mesh are widely used in laparoscopic inguinal hernia repair.

DESIGN

Prospective experimental study.

SETTING

University hospital, The Netherlands.

MATERIAL

Six female Yorkshire & Dutch landway pigs.

INTERVENTION

Laparoscopic transabdominal implantation of six Surgipro meshes and six Prolene meshes in 12 inguinal sites.

MAIN OUTCOME MEASURES

At 3, 6, and 12 weeks after implantation the foreign body reaction was measured by counting multinucleated giant cells at the mesh-tissue interface.

RESULTS

At all times the numbers of multinucleated giant cells at the mesh tissue interface were significantly larger with Surgipro than with Prolene (p < 0.001).

CONCLUSIONS

There is significantly more foreign body reaction after implantation of Surgipro than Prolene mesh.

摘要

目的

比较单丝聚丙烯(普理灵)补片和多丝 Surgipro 补片的异物反应。这两种补片均广泛应用于腹腔镜腹股沟疝修补术。

设计

前瞻性实验研究。

地点

荷兰大学医院。

材料

6 只雌性约克夏和荷兰兰德瑞斯猪。

干预

在 12 个腹股沟部位经腹腔镜经腹植入 6 片 Surgipro 补片和 6 片普理灵补片。

主要观察指标

植入后 3 周、6 周和 12 周,通过计数补片-组织界面的多核巨细胞来测量异物反应。

结果

在所有时间点,Surgipro 补片在补片组织界面的多核巨细胞数量均显著多于普理灵补片(p < 0.001)。

结论

Surgipro 补片植入后的异物反应明显多于普理灵补片。

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