Pike A, Plomin R
Institute of Psychiatry, Denmark Hill, London, U.K.
J Am Acad Child Adolesc Psychiatry. 1996 May;35(5):560-70. doi: 10.1097/00004583-199605000-00010.
To briefly summarize behavioral genetic findings in relation to child and adolescent psychopathology, paying special attention to the environmental rather than genetic components of variation, and to describe recent research exploring specific nonshared environmental processes in the development of adolescent depression.
Behavioral genetic studies of child and adolescent psychopathology were outlined, with special attention given to findings from the Nonshared Environment and Adolescent Development Project. This project was also used to explore maternal negativity as a "candidate" nonshared environmental influence for adolescent depression.
These studies indicate that the environmental factors influencing developmental psychopathology are primarily of the nonshared variety (with the notable exception of juvenile delinquency). In addition, consistent results have not yet emerged from assessments of adolescent depression. Finally, maternal negativity was identified as a specific nonshared environmental factor related to adolescent depression.
The environment as well as genetics is important to understanding childhood psychiatric disorders, and behavioral genetic designs provide the best evidence for this. Specifically, environments not shared by siblings are particularly salient. From a clinical standpoint, these considerations point to the importance of assessing the entire family rather than only the family member with the "problem."
简要总结与儿童和青少年精神病理学相关的行为遗传学研究结果,特别关注变异的环境而非遗传成分,并描述近期探索青少年抑郁症发展中特定非共享环境过程的研究。
概述了儿童和青少年精神病理学的行为遗传学研究,特别关注非共享环境与青少年发展项目的研究结果。该项目还被用于探究母亲的消极情绪作为青少年抑郁症的“候选”非共享环境影响因素。
这些研究表明,影响发展性精神病理学的环境因素主要是非共享性的(青少年犯罪是一个显著例外)。此外,对青少年抑郁症的评估尚未得出一致结果。最后,母亲的消极情绪被确定为与青少年抑郁症相关的特定非共享环境因素。
环境以及基因对于理解儿童精神障碍都很重要,行为遗传学设计为此提供了最佳证据。具体而言,兄弟姐妹不共享的环境尤为突出。从临床角度来看,这些考虑因素表明评估整个家庭而非仅评估有“问题”的家庭成员的重要性。