Hong B K, Jeng C J, Huang S H, Yang Y C, Wang K G
Department of Obstetrics and Gynecology, Li Shin Hospital, Tao-Yuan, Taiwan, R.O.C.
Zhonghua Yi Xue Za Zhi (Taipei). 1996 Mar;57(3):214-8.
Granulosa cell tumor (GCT) accounts for roughly 1.5% of all ovarian neoplasms and 5-10% of ovarian cancers. GCT, which may have profound end-organ effects, has attracted a significant amount of attention despite its rarity. This tumor is rare, and difficult to diagnose before operation. Until now, no specific sonographic findings have been reported.
Twelve cases of pathologically proven GCTs were diagnosed from June 1985 to March 1993. Nine of those cases had preoperative sonographic pictures taken.
Eight out of the nine cases tested exhibited a complex multicystic sonographic pattern. For a case evaluated by a transvaginal color and pulsed Doppler assessment, the blood vessels located in the central part with diffuse dispersed vascular arrangement were found to have a resistance index of 0.38 and a pulsatility index of 0.50. The most common complaints of our patients were postmenopausal bleeding and lower abdominal pain.
We conclude that complex multicystic sonographic features observed by high-resolution ultrasonography, in conjuction with a high preoperative estradiol level and clinical symptoms, may help to establish a preoperative diagnosis of GCT.
颗粒细胞瘤（GCT）约占所有卵巢肿瘤的1.5%，占卵巢癌的5 - 10%。尽管GCT罕见，但因其可能对终末器官产生深远影响，已引起了大量关注。这种肿瘤很罕见，术前难以诊断。迄今为止，尚未有特异性超声表现的报道。
1985年6月至1993年3月期间，经病理证实的颗粒细胞瘤患者共12例。其中9例患者术前进行了超声检查。
9例接受检查的患者中，8例表现为复杂的多囊性超声图像。对于1例经阴道彩色及脉冲多普勒评估的病例，发现位于中央部分、血管呈弥漫性分散排列的血管阻力指数为0.38，搏动指数为0.50。我们的患者最常见的主诉是绝经后出血和下腹痛。
我们得出结论，高分辨率超声检查观察到的复杂多囊性超声特征，结合术前高雌二醇水平及临床症状，可能有助于颗粒细胞瘤的术前诊断。
