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颗粒细胞瘤初次诊断25年后复发。1例病例报告及文献复习。

Recurrence of granulosa cell tumor 25 years after initial diagnosis. Report of a case and review of the literature.

作者信息

Hasiakos D, Papakonstantinou K, Karvouni E, Fotiou S

机构信息

2nd Department of Obstetrics and Gynecology, University of Athens, School of Medicine, Aretaieion Hospital, Athens, Greece.

出版信息

Eur J Gynaecol Oncol. 2008;29(1):86-8.

PMID:18386473
Abstract

Granulosa cell tumors (GCTs) are rare functional sex cord-stromal ovarian tumors constituting approximately 2-3% of all ovarian malignancies. They are characterized by low malignant potential, local spread, late recurrence and high survival rates. We report a case of recurrent ovarian GCT in a 60-year-old woman 25 years after the initial diagnosis. The patient underwent surgical resection of the pelvic masses and refused to receive any adjuvant treatment, considering the late recurrence and high survival rates of this tumor. This case illustrates an example of a very late recurrence and emphasizes the importance of the extended follow-up required for these patients.

摘要

颗粒细胞瘤(GCTs)是罕见的功能性性索间质卵巢肿瘤,约占所有卵巢恶性肿瘤的2%-3%。其特点是恶性潜能低、局部扩散、复发晚且生存率高。我们报告一例60岁女性在初次诊断25年后复发性卵巢颗粒细胞瘤的病例。考虑到该肿瘤复发晚且生存率高,患者接受了盆腔肿块的手术切除,拒绝接受任何辅助治疗。该病例说明了非常晚期复发的一个例子,并强调了这些患者需要延长随访的重要性。

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Extraordinarily Prolonged Disease Recurrence in a Granulosa Cell Tumor Patient.一名颗粒细胞瘤患者出现异常长时间的疾病复发。
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