Sleijfer S, Koops H S, van der Graaf W T
Department of Internal Medicine, University Hospital, Groningen, Netherlands.
Neth J Med. 1996 Mar;48(3):89-91. doi: 10.1016/0300-2977(95)00058-5.
Due to a high incidence of undescended testicles, patients with Down's syndrome have an increased risk of testicular cancer. The treatment of these patients with the successful cisplatin-containing regimens, which are however toxic and require hospitalization, can cause several problems. We present a patient with Down's syndrome suffering from a disseminated seminomatous tumour of the testis who has been successfully treated with combination chemotherapy on an out-patient basis.
由于唐氏综合征患者隐睾症的发病率较高，他们患睾丸癌的风险增加。使用含顺铂的成功治疗方案治疗这些患者，然而这些方案有毒且需要住院，可能会引发一些问题。我们报告了一名患有睾丸播散性精原细胞瘤的唐氏综合征患者，该患者在门诊接受联合化疗后已成功治愈。
