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[法国的冠心病:莫尼卡登记处数据(1985 - 1991年)]

[Coronary disease in France: data from the MONICA registers (1985-1991)].

作者信息

Cambou J P, Arveiler D, Amouyel P, Ruidavets J B, Haas B, Montayé M, Bingham A, Richard J L

机构信息

INSERM U-326-ORSMIP, Toulouse.

出版信息

Rev Epidemiol Sante Publique. 1996;44 Suppl 1:S46-52.

PMID:8935864
Abstract

The MONICA Project is an international project co-ordinated by the World Health Organisation. The objective of this study is to assess fluctuations in coronary heart disease (CHD) mortality and morbidity. From 1985 to 1991 a continuous and exhaustive registration of acute coronary events (15,775 cases among which 12,789 men and 2,986 women) was carried out in the 3 French MONICA Centres Lille, Strasbourg and Toulouse. During this period, the average rate of CHD mortality according to the death certificates was higher for men in Lille (93/100,000 inh) and Strasbourg (84/100,000 inh) than in Toulouse (57/100,000 inh). The official rates are close to those found by the MONICA Registers if documented myocardial infarctions only are taken into account. If sudden deaths are included, these rates must be multiplied by 1.6. In terms of evolution, official statistics showed an improvement with a mortality decrease of 33%. For the MONICA Registers which include sudden deaths, the decrease was only 20%. Official statistics underestimate coronary death rate and overestimate the decrease tendency. Morbidity rates between the South and the North of France are close, and when compared to Northern Europe countries, France is in an area of moderate incidence. The favourable evolution of coronary disease frequency hides in fact a contrasted evolution: improvement in myocardial infarction recurrence and worsening of incidence. The example of CHD proves that registers provide relevant information for a prevention policy.

摘要

莫尼卡项目是一项由世界卫生组织协调的国际项目。本研究的目的是评估冠心病(CHD)死亡率和发病率的波动情况。1985年至1991年期间,法国的三个莫尼卡中心(里尔、斯特拉斯堡和图卢兹)对急性冠状动脉事件进行了持续且详尽的登记(共15775例,其中男性12789例,女性2986例)。在此期间,根据死亡证明计算的冠心病死亡率,里尔(93/10万居民)和斯特拉斯堡(84/10万居民)的男性高于图卢兹(57/10万居民)。如果仅考虑有记录的心肌梗死,官方死亡率与莫尼卡登记处的数据相近。若将猝死纳入计算,这些死亡率须乘以1.6。在演变趋势方面,官方统计显示情况有所改善,死亡率下降了33%。而对于包含猝死情况的莫尼卡登记处数据,下降幅度仅为20%。官方统计低估了冠心病死亡率,高估了下降趋势。法国南北部的发病率相近,与北欧国家相比,法国处于发病率中等的地区。冠心病发病率的有利演变实际上掩盖了一种反差较大的演变情况:心肌梗死复发率有所改善,但发病率却在恶化。冠心病的例子证明,登记处为预防政策提供了相关信息。

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