Chakraborti S K, Dey B K, Ghosh N, Chaudhury A N, Guha Mazumder D N
Department of Gastroenterology, Institute of Post-Graduate Medical Education and Research, Calcutta.
Indian J Gastroenterol. 1996 Apr;15(2):43-5.
Irritable bowel syndrome (IBS) is frequently regarded as a psychological disorder. Data on objective evaluation of psychological abnormalities among IBS patients and control subjects are scanty in our country. We therefore objectively studied patients with IBS.
42 patients satisfying the Manning's criteria and Munich workers' for diagnosis of IBS underwent psychological evaluation using the following tests: a) Eyesenck personality questionnaire. b) State and trait anxiety inventory according to Speilberger's method. c) Hamilton depression rating scale for detection of depression. d) Whitely index of hypochondriasis and discriminant function by Pilowsky's illness behavior questionnaire.
Neuroticism was detected in 76% of IBS patients compared to 9% in control population (p < 0.01). State and trait anxiety scores were 44.5 +/- 17.1 and 49.0 +/- 15.3 respectively in IBS patients; these were higher than those in controls (35.5 +/- 7.5 and 41.2 +/- 6.1 respectively; p < 0.01). Severe depression was observed in 26% of IBS patients and 6% of control subjects (p < 0.05). Significantly higher hypochondriasis score was observed in IBS patients as compared to controls (p < 0.001).
Neuroticism, hypochondriasis and depression were significantly more prevalent in IBS patients attending a clinic, compared to control population.
肠易激综合征(IBS)常被视为一种心理障碍。我国关于肠易激综合征患者和对照人群心理异常客观评估的数据较少。因此,我们对肠易激综合征患者进行了客观研究。
42例符合曼宁标准和慕尼黑工人诊断标准的肠易激综合征患者接受了以下心理评估测试:a)艾森克人格问卷。b)根据斯皮尔伯格方法编制的状态和特质焦虑量表。c)用于检测抑郁的汉密尔顿抑郁评定量表。d)通过皮洛夫斯基疾病行为问卷得出的疑病症惠特利指数和判别功能。
76%的肠易激综合征患者检测出神经质,而对照人群中这一比例为9%(p<0.01)。肠易激综合征患者的状态焦虑得分和特质焦虑得分分别为44.5±17.1和49.0±15.3;高于对照组(分别为35.5±7.5和41.2±6.1;p<0.01)。26%的肠易激综合征患者和6%的对照者观察到严重抑郁(p<0.05)。与对照组相比,肠易激综合征患者的疑病症得分显著更高(p<0.001)。
与对照人群相比,就诊的肠易激综合征患者中神经质、疑病症和抑郁更为普遍。