Barter L S, Watson A D, Maddison J E
Department of Veterinary Clinical Sciences, University of Sydney, New South Wales.
Aust Vet J. 1996 Oct;74(4):277-80. doi: 10.1111/j.1751-0813.1996.tb13774.x.
The degree to which dog owners complied with instructions to administer a 5 to 10 day course of antimicrobial medication to their pets was assessed using microprocessor based monitoring devices. Twenty two clients gave an average of 84% of prescribed doses of amoxycillin-clavulanate. No difference was found between twice and thrice daily dosing regimens in the overall percentage of prescribed doses given. However, timing of doses was far from ideal in many cases and only 34% of doses were given within the designated optimum time period. Adherence to desired dosing intervals tended to be better with twice daily than with thrice daily dosing, although the difference was statistically insignificant.
使用基于微处理器的监测设备评估了狗主人遵照指示给宠物服用5至10天疗程抗菌药物的程度。22位客户平均服用了规定剂量84%的阿莫西林-克拉维酸盐。在每日给药两次和三次的方案中,所给规定剂量的总体百分比没有差异。然而,在许多情况下,给药时间远不理想,只有34%的剂量是在指定的最佳时间段内服用的。每日给药两次时,对期望给药间隔的依从性往往比每日给药三次时更好,尽管差异无统计学意义。