Staddon J M, Rubin L L
Eisai London Research Laboratories Ltd, University College London, UK.
Curr Opin Neurobiol. 1996 Oct;6(5):622-7. doi: 10.1016/s0959-4388(96)80094-8.
The blood-brain barrier regulates the movement of molecules and cells between the circulation and the CNS. Modulation of this barrier may be critical in the aetiology of various CNS pathologies. Endothelial cell tight junctions are an essential part of the barrier, and recent advances have been made in understanding how specific intracellular signalling events regulate cell-cell adhesion and tight-junction permeability.
血脑屏障调节着循环系统与中枢神经系统之间分子和细胞的移动。该屏障的调节在各种中枢神经系统病理学病因中可能至关重要。内皮细胞紧密连接是该屏障的重要组成部分，并且在理解特定细胞内信号事件如何调节细胞间黏附和紧密连接通透性方面已取得了最新进展。
