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Therapeutic horizons for amyotrophic lateral sclerosis.

作者信息

Rothstein J D

机构信息

Department of Neurology, Johns Hopkins University, Baltimore, Maryland 21287, USA.

出版信息

Curr Opin Neurobiol. 1996 Oct;6(5):679-87. doi: 10.1016/s0959-4388(96)80103-6.

Abstract

Recent theories on the pathogenesis of motor neuron disease and research on motor neuron injury have resulted in new putative therapies, which include treatment with various neurotrophic factors, antioxidants and anti-excitotoxicity agents. Clinical and preclinical studies have now provided the first agents that reproducibly alter the course of amyotrophic lateral sclerosis.

摘要

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