未治疗的肺癌：在未进行衰减校正的2-[氟-18]氟-2-脱氧-D-葡萄糖PET扫描上对肿瘤大小和形状的系统变形进行量化

Untreated lung cancer: quantification of systematic distortion of tumor size and shape on non-attenuation-corrected 2-[fluorine-18]fluoro-2-deoxy-D-glucose PET scans.

作者信息

Zasadny K R, Kison P V, Quint L E, Wahl R L

机构信息

Department of Internal Medicine, University of Michigan Medical Center, Ann Arbor 48109-0028, USA.

出版信息

Radiology. 1996 Dec;201(3):873-6. doi: 10.1148/radiology.201.3.8939245.

DOI:10.1148/radiology.201.3.8939245

PMID:8939245

Abstract

The authors quantitatively evaluated possible distortions of tumor size and shape introduced on non-attenuation-corrected 2-[fluorine-18]fluoro-2-deoxy-D-glucose (FDG) positron emission tomography (PET) scans obtained in primary lung cancer tumors. Primary lung cancer tumors in 21 patients were measured on x-ray computed tomography (CT), attenuation-corrected FDG PET, and non-attenuation-corrected FDG PET scans. Apparent anteroposterior tumor dimensions on non-attenuation-corrected FDG PET scans were significantly larger (P = .0007; mean difference, 30%) than on attenuation-corrected FDG PET or CT scans (P = .05; mean difference, 28%). Left-to-right tumor dimensions on non-attenuation-corrected FDG PET scans were significantly smaller than on attenuation-corrected FDG PET scans (P = .03; mean difference, 8.5%) but were not significantly different from those on CT scans (P = .3).

摘要

作者对原发性肺癌肿瘤的非衰减校正2-[氟-18]氟-2-脱氧-D-葡萄糖（FDG）正电子发射断层扫描（PET）中出现的肿瘤大小和形状的可能失真进行了定量评估。对21例患者的原发性肺癌肿瘤进行了X线计算机断层扫描（CT）、衰减校正FDG PET和非衰减校正FDG PET扫描测量。非衰减校正FDG PET扫描上肿瘤的前后径明显大于衰减校正FDG PET或CT扫描（P = .0007；平均差异为30%）（P = .05；平均差异为28%）。非衰减校正FDG PET扫描上肿瘤的左右径明显小于衰减校正FDG PET扫描（P = .03；平均差异为8.5%），但与CT扫描无显著差异（P = .3）。