细胞周期：筛选与破坏。
Cell cycle: cull and destroy.
作者信息
Jackson P K
机构信息
Department of Pathology, Stanford University School of Medicine, Palo Alto, California 94305, USA.
出版信息
Curr Biol. 1996 Oct 1;6(10):1209-12. doi: 10.1016/s0960-9822(96)00697-5.
PMID:8939566
Abstract
A newly discovered family of proteins homologous to yeast Cdc53, called cullins, may play a key role in the targeting of cell-cycle regulators, such as cyclins, for destruction by ubiquitin-dependent proteolysis.
摘要
一个新发现的与酵母Cdc53同源的蛋白质家族，称为cullins，可能在细胞周期调节因子（如细胞周期蛋白）通过泛素依赖性蛋白水解进行降解的靶向过程中起关键作用。
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