转基因动物中的重组蛋白生产。
Recombinant protein production in transgenic animals.
作者信息
Echelard Y
机构信息
Genzyme Transgenics Corporation, One Mountain Road, Framingham, MA 01701-9322, USA.
出版信息
Curr Opin Biotechnol. 1996 Oct;7(5):536-40. doi: 10.1016/s0958-1669(96)80058-9.
PMID:8939621
Abstract
The engineering of animals for recombinant protein production has gone beyond the stage of identifying proper regulatory sequences. Efforts are now spent on the generation of transgenic animals that process heterologous proteins more efficiently. Another line of research is the development of strategies aimed at bypassing pronuclear microinjection.
摘要
通过基因工程改造动物来生产重组蛋白已超越了识别合适调控序列的阶段。目前的工作重点是培育能更高效加工异源蛋白的转基因动物。另一项研究方向是开发旨在绕过原核显微注射的策略。
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