Said S, Benhidjeb T, Jacobi C A, Müller J M
Department of Surgery, University Hospital Charité, Humboldt University of Berlin Schumannstr. 20/21, D-10117 Berlin, Germany.
Surg Endosc. 1996 Dec;10(12):1140-4. doi: 10.1007/s004649900266.
In order to avoid the postoperative complications following conventional surgical treatment of aortoiliac atherosclerotic occlusive disease, a new concept in videoendoscopic vascular surgery on the infrarenal aortoiliacal artery was created.
New instruments for endoscopic vascular surgery were therefore developed. Having elaborated the practicability of "videoendoscopic surgery" in four short-term pilot studies in piglets, we performed a standardized acute study in healthy male piglets (32 +/- 2 kg). Blood flow was monitored ultrasonically in the femoral arteries and systemic and hemodynamic parameters were evaluated in all animals.
The investigation regarding ultrasonically monitored blood flow in the femoral arteries (four aortofemoral bypasses, four iliac patchplasties) and other systemic, hemodynamic parameters after videoendoscopic vascular reconstruction revealed positive results. The following series of standardized long-term animal experiments revealed that 2-7 weeks after the aortofemoral bypass grafting (n = 5), the animals were all doing well. The angiographic examination showed that the prostheses were patent.
Even though it was possible to carry out the endoscopic vascular method according to the rules of conventional vascular surgery, further experimental research and development of endoscopic instruments have yet to be done in order to optimize the new surgical method. This is the subject of our ongoing long-term animal studies.
为避免传统手术治疗主髂动脉粥样硬化闭塞性疾病后的术后并发症，开创了肾下腹主动脉-髂动脉视频内镜血管手术的新概念。
因此研发了用于内镜血管手术的新型器械。在对仔猪进行的四项短期初步研究中阐述了“视频内镜手术”的实用性后，我们对健康雄性仔猪（32±2千克）进行了一项标准化急性研究。对所有动物的股动脉血流进行超声监测，并评估全身和血流动力学参数。
对视频内镜血管重建术后股动脉超声监测血流（四条主动脉-股动脉旁路移植术、四条髂动脉补片成形术）及其他全身、血流动力学参数的研究显示出阳性结果。随后一系列标准化长期动物实验表明，主动脉-股动脉旁路移植术后2至7周（n = 5），动物情况均良好。血管造影检查显示假体通畅。
尽管按照传统血管手术规则实施内镜血管方法是可行的，但为优化这种新手术方法，仍需对内镜器械进行进一步的实验研究和开发。这是我们正在进行的长期动物研究的主题。
