Nelken D
Asthma and Allergy Clinic, Medical Clinic Center, Tel Aviv.
Harefuah. 1996 Sep;131(5-6):164-5, 215.
We treated 14 patients with severe pollinosis or allergic rhinitis with its specific allergen by the sublingual route. Increasing doses of the allergen were given as drops. There was marked improvement in allergic symptoms in 12. Sneezing, itching of the eyes and rhinitis were practically absent, even in the season and there was substantial reduction in intake of antihistamines as well as in the use of steroid inhalers. Only 1 patient did not improve, while 1 developed severe urticaria to Parietaria judaica vaccine.
我们通过舌下途径用特定过敏原治疗了14例重度花粉症或过敏性鼻炎患者。将剂量递增的过敏原制成滴剂给药。12例患者的过敏症状有显著改善。即使在发病季节,打喷嚏、眼睛瘙痒和鼻炎症状基本消失,抗组胺药的摄入量以及类固醇吸入器的使用也大幅减少。只有1例患者没有改善,而1例患者对墙草属疫苗出现了严重荨麻疹。