Nguyen M, McCombs M M, Ghandehari S, Kim A, Wang H, Barsky S H, Love S, Bassett L W
Department of Surgery, UCLA, USA.
Cancer. 1996 Dec 1;78(11):2340-5.
Traditionally, radiologically detected lesions of the breast have been evaluated by open surgical biopsy with wire localization. Recently, core needle biopsy has been introduced as an alternative to open surgical biopsy. The authors evaluated their own results with long term follow-up after core needle biopsy and reviewed the experience of other physicians with this new technique.
Four hundred thirty-one core needle biopsies performed at UCLA were analyzed. The outcome of these cases was determined by either surgery or long term follow-up. Statistical analysis was performed to determine the accuracy of the method.
Definitive outcome was obtained in 96% of the core needle biopsy cases, with a median follow-up time of 18 months (range, 6-38 months). The authors achieved a sensitivity of 99% and a specificity of 100%. The false-negative rate was 1.7%. There were no complications in this series.
Core needle biopsy is a highly accurate and safe method for the diagnosis of radiologically detected lesions of the breast.
传统上，乳腺影像学检查发现的病变通过金属丝定位开放手术活检进行评估。最近，粗针活检已被引入作为开放手术活检的替代方法。作者评估了粗针活检后长期随访的自身结果，并回顾了其他医生使用这种新技术的经验。
分析了在加州大学洛杉矶分校进行的431例粗针活检。这些病例的结果通过手术或长期随访确定。进行统计分析以确定该方法的准确性。
96%的粗针活检病例获得了明确结果，中位随访时间为18个月（范围6 - 38个月）。作者实现了99%的敏感性和100%的特异性。假阴性率为1.7%。该系列中无并发症发生。
粗针活检是诊断乳腺影像学检查发现病变的一种高度准确且安全的方法。
