Hu Y, Hoffman D I, Maxson W S, Ory S J
Northwest Center for Infertility and Reproductive Endocrinology, Margate, Florida 33063, USA.
Fertil Steril. 1996 Dec;66(6):991-4.
To evaluate the effect of nonselective assisted hatching on pregnancy rate (PR) and to provide an alternative and simplified method for clinical application of assisted hatching.
Retrospective analysis of clinical data.
Private infertility practice.
PATIENT(S): Women from 258 consecutive stimulated IVF cycles.
INTERVENTION(S): Assisted hatching was performed on each transferred embryo regardless of patient history, embryo morphology, or other selection criteria routinely applied to many IVF programs.
MAIN OUTCOME MEASURE(S): Pregnancy, live birth, and implantation rates.
RESULT(S): Of 258 consecutive patients who had nonselective assisted hatching, 109 (42%) had clinical pregnancies, with 93 (36%) live births and 178 (20%) embryos implanted.
CONCLUSION(S): Nonselective assisted hatching resulted in an acceptable PR and provided an alternative and simplified method for clinical application of assisted hatching.
评估非选择性辅助孵化对妊娠率（PR）的影响，并为辅助孵化的临床应用提供一种替代且简化的方法。
临床数据的回顾性分析。
私立不孕不育诊所。
来自连续258个刺激体外受精周期的女性。
对每个移植胚胎进行辅助孵化，不考虑患者病史、胚胎形态或许多体外受精项目常规应用的其他选择标准。
妊娠率、活产率和着床率。
在连续258例接受非选择性辅助孵化的患者中，109例（42%）临床妊娠，93例（36%）活产，178枚（20%）胚胎着床。
非选择性辅助孵化导致了可接受的妊娠率，并为辅助孵化的临床应用提供了一种替代且简化的方法。
