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脱钙冻干骨移植对囊肿摘除术后颌骨缺损愈合的影响。

Effect of decalcified freeze-dried bone allograft on the healing of jaw defects after cyst enucleation.

作者信息

Bodner L

机构信息

Department of Oral and Maxillofacial Surgery, Soroka Medical Center, Ben-Gurion University of the Negev, Beer-Sheva, Israel.

出版信息

J Oral Maxillofac Surg. 1996 Nov;54(11):1282-6. doi: 10.1016/s0278-2391(96)90482-6.

DOI:10.1016/s0278-2391(96)90482-6
PMID:8941177
Abstract

PURPOSE

This study radiographically evaluated the changes that occur in jaw defects after enucleation of cysts and either grafting with demineralized freeze-dried bone allograft (DFDBA) or packing with absorbable gelatine sponge (Gelfoam).

PATIENTS AND METHODS

Thirty-two patients (14 males, 18 females) with cystic lesions of the jaws were divided into two groups. Group A underwent enucleation and bone grafting with DFDBA. Group B underwent enucleation and packing with Gelfoam. Both groups were evaluated radiographically before surgery, immediately postoperatively, and 6, 12, 24, and 36 months postoperatively. The density of the area was measured with a digital densitometer.

RESULTS

The density in group A was significantly (P < .05 to .01) greater than in group B at 6 and 12 months postoperatively. The difference at 24 months was not significant. Group A reached density levels at 6 months that were reached by group B at 12 months.

CONCLUSION

The findings demonstrate that decalcified freeze-dried bone allograft enhances bone healing in jaw defects after cyst removal.

摘要

目的

本研究通过影像学评估囊肿摘除术后颌骨缺损采用脱矿冻干同种异体骨(DFDBA)移植或用可吸收明胶海绵(明胶海绵)填塞后发生的变化。

患者与方法

32例颌骨囊性病变患者(男14例,女18例)分为两组。A组行囊肿摘除术并用DFDBA进行骨移植。B组行囊肿摘除术并用明胶海绵填塞。两组均在术前、术后即刻以及术后6、12、24和36个月进行影像学评估。用数字密度计测量该区域的密度。

结果

术后6个月和12个月时,A组的密度显著高于B组(P <.05至.01)。24个月时差异不显著。A组在6个月时达到的密度水平与B组在12个月时达到的密度水平相同。

结论

研究结果表明,脱钙冻干同种异体骨可促进囊肿切除术后颌骨缺损的骨愈合。

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