Bodner L
Department of Oral and Maxillofacial Surgery, Soroka Medical Center, Ben-Gurion University of the Negev, Beer-Sheva, Israel.
J Craniomaxillofac Surg. 1998 Apr;26(2):116-20. doi: 10.1016/s1010-5182(98)80051-6.
Osseous defects of the jaws following trauma, congenital deformity or pathology may show poor osteogenesis and the affected area may never be completely replaced by bone or will show alveolar height loss. The purpose of the present study was to evaluate the effect of allogenic bone implants (ABI) on the osteogenesis of jaw defects. Fifty-two patients (27 males, 25 females) with cystic lesions of the jaws were randomly divided into two groups: Group A underwent enucleation and packing with adsorbable gelatine sponge. Group B underwent enucleation and grafting with ABI. Both groups were evaluated radiographically. The height of the alveolar process was measured directly on the radiography. The density was measured with a digital densitometer. In Group A, the mandibular height at 6, 12 and 24 months postoperatively was 88%, 80% and 78% of the preoperative heights, respectively. In Group B, the heights were 95%, 93% and 90%, respectively. These differences were significant (P < 0.05-0.01). The density in Group B was significantly greater (P < 0.05-0.01) than in Group A at 6 and 12 months postoperatively. The difference at 24 months was not significant. On the basis of these findings, it can be concluded that ABI grafting of jaw defects enhances osteogenesis and prevents alveolar height loss in the mandible. ABI represent an encouraging alternative to autogenous bone grafting.
创伤、先天性畸形或病理因素导致的颌骨骨缺损可能显示成骨不良，且受影响区域可能永远无法完全被骨替代，或者会出现牙槽嵴高度降低。本研究的目的是评估同种异体骨植入物（ABI）对颌骨缺损成骨的影响。52例颌骨囊性病变患者（男27例，女25例）被随机分为两组：A组行囊肿摘除术并用可吸收明胶海绵填充。B组行囊肿摘除术并植入ABI。两组均进行影像学评估。直接在X线片上测量牙槽突的高度。用数字密度计测量密度。A组术后6个月、12个月和24个月时下颌高度分别为术前高度的88%、80%和78%。B组的高度分别为95%、93%和90%。这些差异具有统计学意义（P<0.05 - 0.01）。术后6个月和12个月时，B组的密度显著高于A组（P<0.05 - 0.01）。24个月时差异无统计学意义。基于这些发现，可以得出结论，颌骨缺损的ABI植入可增强成骨并防止下颌牙槽嵴高度降低。ABI是自体骨移植的一种令人鼓舞的替代方法。
