Rummelhart J M, Mellonig J T, Gray J L, Towle H J
Naval Dental Clinic, San Diego, CA.
J Periodontol. 1989 Dec;60(12):655-63. doi: 10.1902/jop.1989.60.12.655.
This study was conducted to clinically compare freeze-dried bone allograft (FDBA) and demineralized freeze-dried bone allograft (DFDBA). Twenty-two defects (11 intrapatient pairs) in 9 patients were grafted with either DFDBA or FDBA. Evaluations were based on standardized radiographs, presurgical and postsurgical soft tissue measurements using the cemento-enamel junction as a fixed reference point, and osseous measurements at the time of surgery. Grafted sites were re-entered at a minimum of 6 months following placement. A mean osseous repair of 1.7 mm (59%) occurred with DFDBA and 2.4 mm (66%) with FDBA. A mean clinical attachment gain of 1.7 mm was obtained with DFDBA and 2.0 mm with FDBA. Probing depths decreased a mean of 2.00 mm with both DFDBA and FDBA. These findings reveal no significant differences between the two materials in primarily intraosseous defects when evaluated at a minimum 6 months postsurgery.
本研究旨在对冻干骨同种异体移植（FDBA）和脱矿冻干骨同种异体移植（DFDBA）进行临床比较。9例患者的22处骨缺损（11对患者自身对照）分别采用DFDBA或FDBA进行移植。评估基于标准化X线片、以牙骨质-釉质界作为固定参考点的术前和术后软组织测量，以及手术时的骨测量。移植部位在植入后至少6个月再次切开。DFDBA的平均骨修复为1.7 mm（59%），FDBA为2.4 mm（66%）。DFDBA的平均临床附着获得为1.7 mm，FDBA为2.0 mm。DFDBA和FDBA的探诊深度平均均降低2.00 mm。这些结果表明，在术后至少6个月进行评估时，这两种材料在原发性骨内缺损方面无显著差异。
