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系统性红斑狼疮的预后与治疗

Prognosis and treatment of systemic lupus erythematosus.

作者信息

Gladman D D

机构信息

University of Toronto, Centre for Prognosis Studies in the Rheumatic Diseases, Toronto Hospital, Ontario, Canada.

出版信息

Curr Opin Rheumatol. 1996 Sep;8(5):430-7. doi: 10.1097/00002281-199609000-00007.

DOI:10.1097/00002281-199609000-00007
PMID:8941446
Abstract

This article summarizes the evidence for the improved prognosis in patients with systemic lupus erythematosus (SLE). It discusses the reasons for improved survival, as well as the risk for mortality, which still remains high for patients with this disease. Causes of death are reviewed, and prognostic factors examined. Other outcome measures for prognosis in SLE, including specific organ damage, accumulated damage index, and health status and quality of life are considered. Recent articles on therapy for SLE are discussed.

摘要

本文总结了系统性红斑狼疮(SLE)患者预后改善的证据。讨论了生存率提高的原因以及死亡率风险,对于该疾病患者而言,死亡率仍然很高。回顾了死亡原因并检查了预后因素。还考虑了SLE预后的其他结局指标,包括特定器官损伤、累积损伤指数以及健康状况和生活质量。讨论了近期关于SLE治疗的文章。

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