Kettmann V, Drímal J, Svétlík J
Department of Analytical Chemistry, Faculty of Pharmacy, Comenius University, Bratislava, Slovak Republik.
Pharmazie. 1996 Oct;51(10):747-50.
The affinity of two compounds, closely related to 1,4-dihydropyridines, was determined in competition binding experiments using canine cerebral cortex membranes and [3H]nitrendipine as a radioligand. Some aspects of structure-affinity relationships are discussed in relation to existing models of the dihydropyridine binding site.
在使用犬大脑皮层膜和[3H]尼群地平作为放射性配体的竞争结合实验中，测定了两种与1,4 - 二氢吡啶密切相关的化合物的亲和力。结合二氢吡啶结合位点的现有模型，讨论了结构 - 亲和力关系的一些方面。
